Figure 1.
Cold preservation most severely affects the sinusoidal microvasculature,
whereas the endothelial cells lining the larger vessels and the hepatocytes
and bile ducts are less severely affected. This is a plastic-embedded
thick tissue section of a liver biopsy obtained after cold preservation,
just prior to implantation in the recipient. In this case, the endothelial
cells lining the portal vein and sinusoids(arrow) show only mild injury,
because most are elongated and attached to the underlying connective
tissue.
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