Acute Antibody Mediated Rejection of Allograft Liver.
This patient received a living related liver transplant for relief of NASH cirrhosis. Postoperative course was notable for declining mental status which was complicated by cardiac arrest during a diagnostic procedure. The specimen is from the allograft hepatectomy.
The H&E stain shows evidence of acute antibody-mediated rejection. C4d Immunostain shows uptake in the portal microvasculature and CD3 stain highlights T lymphocytes that generally spare bile ducts. Features of acute AMR and the current grading system are available here.
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Last Modified:Thu Jul 19 2018
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