Includes Polymorphic Hyperplasia
and Lymphoma of Frizzera
et al.
Minimally Polymorphic PTLD
Minimal
Prominent
Variable
Disrupted
18/22 (82%) with Monoclonal component
Term not widely applied; synonymous with plasmacytoma
Monomorphic PTLD
None
Rare to None
Variable
Disrupted
5/5 (100%) Monoclonal
Synonymous with non-Hodgkin's
lymphomas
Notes: *Early
infiltrative lesions may not have recognizable architectural destruction;
#Clonal composition was based on molecular or immunoperoxidase
studies in individual cases.
Reference
Nalesnik
MA, Jaffe R, Starzl TE, Demetris AJ, Porter K, Burnham JA, Makowka L, Ho M, Locker J: The pathology of posttransplant lymphoproliferative disorders occurring in the setting of Cyclosporine A-Prednisone immunosuppression.
Am J Pathol 133:173-192, 1988
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