1a. | Fragments of small bowel | ( ) |
1b. | Fragments of non-small bowel (if present) | ( ) |
2. | Architectural distortion | ( )Norm | ( ) Indeter | ( ) Mild | ( ) Mod | ( ) Sev |
| | if distorted, by: | ( ) Villous blunting | ( ) Mucosal atrophy | ( ) Mucosal erosion | ( ) Ulceration | ( ) Inflammation | ( ) Granulation tissue | ( ) Regeneration | ( )Gland disarray |
3. | Surface and/or crypt epithelial injury | ( ) Yes | ( ) No |
4. | Surface and/or crypt apoptosis | ( ) apoptotic bodies/10 crypts |
5. | Surface and/or crypt mitoses | ( ) Yes | ( ) No | ( ) N/A |
6. | Surface and/or crypt epithelial inflammation | ( ) Yes | ( ) No |
| if Yes, check 6a-6b |
| | 6a. Number of inflammatory cells/crypt | ( ) 2-4 | ( ) 5-10 | ( ) >10 |
| | 6b. Type | ( ) Mononuclear | ( ) Neutrophils | ( ) Eosinophils |
7. | Mucosal erosion/ulceration | ( ) Yes | ( ) No |
8. | Luminal inflammatory infiltrate | ( ) Yes | ( ) No |
9. | Lamina propria inflammation | ( ) Yes | ( ) No |
| if Yes, check 9a-9c |
| | 9a. Severity | ( ) Mild | ( ) Mod | ( ) Sev |
| | 9b. Type | ( ) Mononuclear | ( ) Neutrophils | ( ) Eosinophils |
| | 9c. Subendothelial "endothiliitis" | ( ) Yes | ( ) No |
10. | Lamina propria fibrosis | ( )Norm | ( ) Mild | ( ) Mod | ( ) Sev |
11. | Granulation tissue | ( ) Yes | ( ) No |
12. | Granulomatous inflammation | ( ) Yes | ( ) No |
13a. | Ischemic necrosis | ( ) Yes | ( ) No |
13b. | Muscle wall necrosis | ( ) Yes | ( ) No |
14. | Lymphoid aggregates | ( ) Yes | ( ) No |
15. | Obliterative arteriopathy | ( ) Yes | ( ) No | ( ) No artery for evaluation |
16. | Intravascular thrombi | ( ) Yes | ( ) No |
17. | Infiltrates suggestive of PTLD | ( ) Yes | ( ) No |
18. | Infectious agents | ( ) Yes | ( ) No |
| if Yes, specify: | ( ) CMV | ( ) HSV | ( ) EBV | ( ) Adenovirus | ( ) Candida | ( ) Others |
19. | Other findings: | |
20. | Diagnostic categories (check as many as appropriate) | ( ) No pathologic change |
| | ( ) Preservation injury |
| | ( ) Nonspecific inflammation |
| | ( ) Ischemic change |
| | ( ) Regenerative changes |
| | ( ) Acute rejection | ( ) Indeter | ( ) Mild | ( ) Mod | ( ) Sev |
| | | check if followup | ( ) resolving | ( ) similar | ( ) worsening |
| | ( ) Chronic rejection |
| | ( ) Ulceration, cause uncertain |
| | ( ) CMV | ( ) EBV | ( ) HSV | ( ) Adenovirus | ( ) Cryptosporidium |
| | ( ) Bacterial overgrowth |
| | ( ) Pseudomembranous colitis |
| | ( ) PTLD |
| | ( ) Vascular thrombosis (specify) |
| | ( ) Miscellaneous |