Figure 1. The earliest changes associated with the onset of acute viral type B hepatitis in a liver allograft are usually found within the lobules. There is disarray, Kupffer's cell hypertrophy, spotty acidophilic necrosis of hepatocytes and lobular inflammation of variable intensity. The inset shows staining for HBcAg. Note the nuclear and focal cytoplasmic positivity.

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Last Modified: Thu Jun 18 10:14:08 EDT 2009


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