Figure 6.
Immunofluorescence showing linear IgG deposits within tubular
basement membranes(TBM) in a patient with chronic transplant
glomerulopathy and severe tubular atrophy. Circulating anti-TBM
antibodies are demonstrable in 3% of renal transplant recipients,
but these are believed to be a secondary response to tubular antigens
released by ischaemically injured tissue. Immunoglobulin trapping
within atrophic tubules lesion is probably a non-specific phenomenon.
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