Heart Allograft Biopsy Interpretation

Figure 9. The hypothesis that Quilty lesions are a site of antigen processing and low grade immune stimulation(1) is supported by the observation that they can contain germinal centers(outlined by arrows) or secondary lymphoid follicles, as shown in the photomicrograph.


  1. Demetris AJ, Murase N, Ye Q, Galvao FHF, Richert CA, Saad R, Pham S, Duquesnoy RJ, Zeevi A, Fung JJ, Starzl TE, Analysis of Chronic Rejection and Obliterative Arteriopathy: possible contributions of donor antigen presenting cells and lymphatic disruption. Amer J Pathol 1997;(in press).

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Last Modified: Mon Aug 24 8:00:00 EDT 2009