- Late Bile Duct and Parenchymal Changes in Chronic Liver Allograft
Rejection
-
In the later stages of chronic rejection, there may be only
mild or even no portal inflammation. Bile ducts loss affects > 50 % of the portal
tracts, and any remaining ducts usually continue to show
atrophy and pyknosis. Within the lobules, cholestasis, foam cell clusters and moderate to severe (bridging)
perivenular fibrosis appear. However, a classic cirrhosis, with portal-to-portal bridging fibrosis; fibrous septae
containing proliferating cholangioles; and regenerative nodules is uncommon in our experience.
Please mail comments, corrections or suggestions to the
TPIS administration at the UPMC.
[FRAMES]
[NO FRAMES]