Humoral Rejection

Humoral Rejection
Widespread hemorrhagic necrosis like that shown above, is characteristic of severe humoral rejection. However, this degree of damage is not commonly encountered unless the recipient receives recipient-compatible blood products that contain a large amount of anti-donor antibodies. This passively administered antibody can continue to fuel the humoral rejection reaction. For example, this O recipient of an A liver received 30 units of type O blood. It likely contained enough anti-A antibodies to make the reaction much worse than it might have otherwise been.


Please mail comments, corrections or suggestions to the TPIS administration at the UPMC.

Last Modified: Thu Jun 18 10:14:08 EDT 2009