Compared to other solid organ allografts,
Toxoplasmosis gondii is a parasitic infection that is more
common in heart allograft biopsies than in liver or kidney
sample. This is likely related to the cardiac myocytes serving as
a site of latency. In the example shown above, there is no
significant inflammation associated with the infected cell(arrow).
A higher magnification shows in greater detail the small basophilic to
amphophilic tachyzoites present in the myocyte(inset, upper
left). Immunoperoxidase staining for Toxoplasmosis can be
used to further substantiate the diagnosis(inset, lower left).