Contributed by Samuel A.
Yousem, M.D.
PATIENT HISTORY:
The patient is a 36 year old white male. History of double lung
transplant for cystic fibrosis. History of ACR grade III, in
8/96. Decreased breath sounds in right lung otherwise stable
with scattered wheezing.
Final Diagnosis (Case 1)
ALLOGRAFT LUNG, SITE UNSPECIFIED, TRANSBRONCHIAL BIOPSY -
- MILD ACUTE CELLULAR REJECTION WITH LARGE AIRWAY
INFLAMMATION. NO SMALL AIRWAYS PRESENT TO EVALUATE
BRONCHIOLITIS OBLITERANS (A2c/A2B2).
- ALVEOLAR HEMOSIDEROSIS WITH INTERSTITIAL CALCIFICATIONS.
Previous Biopsies on this Patient:
NONE
TPIS Related Resources:
Lung Allograft Biopsy Rejection
Criteria
Lung Transplant Topics
Gross Description - Case 1
The specimen is received in saline labeled "transbronchial
biopsy". Received are four irregular fragments of tan-pink, soft
tissue, these range from less than 0.1 to 0.1 cm. in greatest
dimension. Additionally received are five irregular portions of
clotted, dark red-brown blood. These range from 0.1 to 0.4 cm.
in greatest dimension.
Microscopic Description - Case 1
The microscopic examination substantiates the diagnosis.
Please mail comments, corrections or suggestions to the
TPIS administration at the UPMC.
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