Figure 10. Recurrent cirrhosis because of chronic type B viral hepatitis in an allograft rarely if ever results in a macronodular pattern. Instead the cirrhosis that develops assumes a micronodular appearance. This may be related to several changes in the pathogenesis of cirrhosis induced by immunosuppression and MHC mismatching. Compare this cirrhotic liver to the one shown in Figure L, which is the original or native liver removed at the time of the initial liver transplant. It shows a macronodular cirrhosis.