Contributed by Parmjeet S.
Randhawa, MD
PATIENT HISTORY:
The patient is a 63 year old male status post orthotopic heart
transplant.
Final Diagnosis (Case 1)
ALLOGRAFT HEART, ENDOMYOCARDIAL BIOPSY -
- FOCAL MILD ACUTE CELLULAR REJECTION (GRADE 1A).
Previous Biopsies on this Patient:
NONE
TPIS Related Resources:
Heart Allograft Biopsy Grading
Schema
Heart Transplant Topics
Gross Description - Case 1
The specimen is received in buffered formalin labeled
"endomyocardial biopsy tissue" and consists of four irregular
portions of tan to white soft tissue, ranging from 0.2 to 0.3 cm.
in greatest dimension.
Microscopic Description - Case 1
Three fragments of myocardium with a mild mononuclear
infiltrate in an endocardial, perivascular and interstitial
location. Myocyte injury is not identified. No infectious
agents seen. Endocardial and interstitial fibrosis is present.
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TPIS administration at the UPMC.
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