Contributed by Michael A. Nalesnik, M.D.
PATIENT HISTORY:
Per referral information sheet, the patient is an elderly male with a pre-op diagnosis of liver mass. Review of outside material.

Final Diagnosis (Case 76)

NATIVE LIVER, NEEDLE BIOPSY -
    SUSPICIOUS FOR MALIGNANCY.

Comment:
The immunocytochemical stains are consistent with this interpretation.The case has also been reviewed by Dr. N. Paul Ohori who agrees with this interpretation.

Previous Biopsies on this Patient:
None

TPIS Related Resources:
Liver Transplant Topics

None.

Gross Description - Case 76

The specimen consists of two (2) paraffin blocks. No surgical pathology report is received with the specimen.

Microscopic Description - Case 767

The specimen consists of two portions of fine needle aspiration biopsy. Both are characterized by extensive hemorrhage and blood elements with scanty epithelial and stromal cells. In one slide (labeled 1A) a small nest of epithelial cells with eosinophilic cytoplasm, round to irregular nuclei, and moderately prominent nucleoli are seen. The cells resemble hepatocytes. Elsewhere is seen stromal elements and occasional smaller cells resembling biliary epithelium. The special stains are performed and the results are as follows:

Alpha-feto-protein - negative
Factor 13 - +/-
Lewis X antigen - negative
Leu M1 - positive
B72.3 - negative
Alpha-1-antitrypsin - heavy background stain
Polyclonal CEA - +/-

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