Contributed by Randall G. Lee, M.D.
PATIENT HISTORY: Per referral letter, the patient is a 41-year-old female who suffers from breast cancer. During her evaluation, she was found to have a 1.5 cm. nodule on the free edge of the liver (by radiograph). Review of outside material.

Final Diagnosis (Case 39)

LIVER, LAPAROSCOPIC BIOPSY -
  1. BENIGN HEPATOCELLULAR NEOPLASM CONSISTENT WITH HEPATIC ADENOMA.
  2. MARGINS OF RESECTION AND BACKGROUND LIVER CANNOT BE EVALUATED.

Previous Biopsies on this Patient:
None

TPIS Related Resources:
Knodell Scoring
Liver Transplant Topics

Gross Description - Case 39

The specimen consists of four (4) consult slides . No surgical pathology report is received with the specimen.

Microscopic Description - Case 39

The sections show fragments of a benign hepatocellular neoplasm characterized by the absence of normal lobular landmarks, the presence of scattered aberrent arteries, and the proliferation of cytologically bland liver cells in plates of one to two cell thickness. Some fragments also show multiple efferent veins in abnormal relationships. The liver cells show mild macrovesicular steatosis, but no nuclear atypia, mitoses, or evidence of invasion are identified. These changes are consistent with a hepatic adenoma, and a clinical history of oral contraceptive or other steroid use would be of interest. No evidence of metastatic breast carcinoma is seen.

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