Humoral Rejection
Small areas of hepatocyte necrosis usually begin to appear between 6 and 24 hours after transplantation in presensitized recipients. In clinical samples, this is usually one of the first reliable and reproducible observations that suggest a untoward reaction in such patients. When this situation is encountered, it is important to check the class and titer of the preformed antibodies, the complement levels and the persistence of the antibodies after transplantation.


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