Previous Biopsies on this Patient:
[See Case 1]
TPIS Related Resources:
Small Bowel Transplant Topics
(2 HE) The normal small intestinal architecture is largely intact. Long and delicate villi are recognized. Some of the surface epithelium is focally denuded, which appears to be artefactual. In most regions, there is no underlying neutrophil congestion, nor necrosis, which otherwise might be expected. However, very slight and focal neutrophil sludging and red cell congestion are seen in one area. There is no significant mononuclear inflammatory cell infiltrate and no evidence of crypt infiltration or damage is seen. There is less than one apoptotic body per ten crypts. Lymphocytes and plasma cells normally present in the lamina propria appear small and inactive. No viral inclusions are seen.
Overall, the histopathologic findings are relatively mild and non-specific. There is no definite evidence of acute rejection, nor significant immune activation. The focal neutrophil sludging and congestion may be related to the biopsy procedure.