Recurrent Renal Disease

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Membranoproliferative Glomerulonephritis

Membranoproliferative glomerulonephritis is characterised by expansion of the mesangium with varying degrees of mesangial proliferation. The glomerular capillary loops become patchily thickened and show a double contour on silver stains. Electron microscopy reveals interposition of mesangial cell processes between the epithelial and endothelial sides of the GBM, and characteristic sub-endothelial electron dense deposits.

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Last Modified: Thu Jun 18 10:14:08 EDT 2009