Figure 2.
In this photomicrograph there is low grade mononuclear lobular
inflammation, typical of EBV-related hepatitis, like that seen in the general
population with hepatitis related to infectious mononucleosis. Note the slight
increase in sinusoidal lymphocytes and "indian-filing" along the sinusoids.
This histopathological presentation is extremely difficult to differentiate from
non-specific viral hepatitis or low grade viral hepatitis type B or C in an
allograft recipient. The diagnosis of EBV hepatitis can be confirmed or
excluded with the use of in situ hybridization for EBV EBER RNA.
Please mail comments, corrections or suggestions to the
TPIS administration at the UPMC.