Hepatic artery thrombosis, particularly within the first few weeks
after liver transplantation when the allograft is devoid of collateral arterial
circulation, results in necrosis of the large bile ducts. The necrotic tissue,
particularly in and around the biliary tree, is fertile soil for the growth of
fungi and bacteria. When such tisue is encountered, a gram and grocott stain
should be routinely examined. This photomicrograph of a Grocott(Methenamine
silver stain) highlights the pseudohyphae, typical of Candida infection, which
invade a necrotic bile duct after hepatic artery thrombosis.