A severe preservation-related insult, results within 2-3 days
after transplantation in a ductular reaction in the periportal
region. The cells appear to sprout from the near the canals
of Herring and mostly show features of biliary epithelial
differentiation. Sometimes this reaction produces histopathological
changes that can be misinterpreted as biliary tract obstruction.
However, the lack of periductal edema and neutrophils, involving
the true bile duct in the middle of the portal connective tissue,
argues against the diagnosis of biliary obstruction in this case.