The diagnosis of humoral liver allograft rejection is difficult to
establish with certainty, and is often one of exclusion, where other
causes injury are reasonably excluded. Therefore, it is important
establish that the donor liver was normal at the time of implantation.
This is most often accomplished by a "backtable" biopsy, taken
after harvesting, but before implantation into the recipient.
In this biopsy, note the intact lobular architecture, and
absence of significant pathological changes.