Heart Allograft Biopsy Interpretation

Figure 5. Previous biopsy sites are seen in up to 30% or more of endomyocardial biopsies obtained within the first 30 days after transplantation. If they are sampled soon after the previous biopsy, partially organized fibrin masses are usually detected. However, if they are sampled more than several months after the previous biopsy, there may only be a focal area of fibrosis, accompanied by pigmented macrophages, plasma cells and occasional lymphocytes. The key identifying feature however, is the presence of myofiber disarray at the base of the lesion(arrow).

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Last Modified: Mon Aug 24 8:00:00 EDT 2009